The colon exhibits the highest microbial density, reaching up to 10 anaerobic bacteria per gram of luminal content (210)
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Detailed mechanisms are portrayed in Figure 5
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Abstract Chronic inflammation in type 2 diabetes (T2D), characterized by constitutively activated immune cells and elevated pro-inflammatory mediators along with hyperglycaemia and increased free fatty acids and branched chain amino acid levels, significantly alters the immuno-metabolic axis
The most likely explanation involves indirect mechanisms, particularly dehydration and electrolyte imbalances resulting from common gastrointestinal side effects like nausea, vomiting, and diarrhoea