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Teduglutide (Gattex) is the FDA-approved GLP-2 receptor agonist, indicated for short bowel syndrome a niche gastrointestinal condition

What Clinical Trials Show About Semaglutide and Heartburn Major semaglutide trials like STEP 1 and STEP 2 documented nausea, vomiting, and constipation as the most common gastrointestinal side effects, affecting 2030% of participants