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Meijerink AM, Van Rijssel RH, Van Der Linden PJQ

The copper centers of complex IV are critical in the reduction of the oxidized iron (ferric iron: Fe 3+ ) of cytochrome c which was oxidized by the electrons from complex III

Similarly, the STEP 4 trial found that patients who discontinued semaglutide and switched to a placebo for 48 weeks regained 6.9% of their body weight

A conservative estimate suggests that a 50-pound weight regain costs $5,000 to $15,000 in direct healthcare costs over the following five years through increased medications, more frequent provider visits, and management of weight-related complications

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J Headache Pain 63(5):601610 Zelissen PM et al (1991) Calcitonin gene-related peptide in human obesity