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Introduction to Small Molecule Drug Discovery and Preclinical Development

found that the antitumor drug erastin induces unique iron dependent non-apoptotic cell death in Ras mutant tumors

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Lam CSP, Ramasundarahettige C, Branch KRH et al (2022) Efpeglenatide and clinical outcomes with and without concomitant sodium-glucose cotransporter-2 inhibition use in type 2 diabetes: exploratory analysis of the AMPLITUDE-O trial

In contrast, BRP appears to act specifically in the hypothalamus, which controls appetite and metabolism. Svensson is the senior author of the study, published March 5, 2025, in Nature

Still, the SELECT trial does not mean every GLP-1 medication has the same cardiovascular outcome data, every patient qualifies for cardiovascular-risk reduction treatment, or GLP-1 therapy replaces standard heart-disease prevention