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Figure 2: Changes in body weight from baseline to the end of treatment at week 26 associated with the treatment policy estimand, in the randomly assigned treatment groups administered either 0.3 mg of cagrilintide, 0.6 mg of cagrilintide, 1.2 mg of cagrilintide, 2.5 mg of cagrilintide, 4.5 mg of cagrilintide, 3.0 mg of liraglutide, or a placebo

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The TSC complex, consisting of TSC1 and TSC2, interacts with GTPase-Ras, acting as a negative regulator of mTOR activity (47)

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The result is a once-weekly subcutaneous injection that maintains steady appetite-regulating activity throughout the dosing period