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The in vitro and in vivo depigmenting activity of pterostilbene through induction of autophagy in melanocytes and inhibition of UVA-irradiated -MSH in keratinocytes via Nrf2-mediated antioxidant pathways

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Affected patients present with metabolic acidosis, hypoketotic hypoglycemia, hypotonia, lethargy, convulsions and coma

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It peaks around day 2 to 3