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The oxidative stress of Hcy in the MTHFR genotype, the residual spike protein S in LC, and reactivated viruses due to persistent lymphopenia conspire to overwhelm mitochondria lacking an antioxidant shield

N Engl J Med 375(4):311322 Marso SP, Bain SC, Consoli A, Eliaschewitz FG, Jodar E, Leiter LA et al (2016) Semaglutide and cardiovascular outcomes in patients with type 2 diabetes

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In the forecast analysis of obesity trajectories published in The Lancet in March 2025, it is predicted that by 2050, up to 2 in 3 adults over 25 years will be overweight or obese (Ng et al

This expands the role of these medications far beyond obesity treatment

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