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The enzyme isoform, prostaglandin H 2 synthase-2, may mediate vascular dysfunction under oxidative stress conditions

Local side effects: Common local side effects of nasal spray may include temporary nasal irritation or dryness, and occasional nosebleeds with prolonged or excessive use [14]

New England Journal of Medicine, 375(4), 311-322

It is suitable for patients who have severe or recurrent hyperthyroidism, who cannot tolerate or are allergic to anti-thyroid drugs, or who do not want surgery

While L-Carnitine is generally considered safe, excessive consumption may lead to nausea, vomiting, and diarrhea

PMID: 30915550 Malinda KM, et al