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In an ischemic stroke mouse model, reactive astrocytes were linked to vascular repair, as they increased the expression of genes related to angiogenesis

Each member of the treatment groups received an icv injection of scopolamine hydrobromide (70 nmof in 2 aCSF over a duration of 20 s) 20 min prior to testing followed by Dihexa (300 pmol in 2 aCSF), Hinge (300 pmol in 2 aCSF), or Hinge + Dihexa (300 pmol in 4 aCSF) 5 min prior to testing

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Importantly, oxidative damage caused by the production of ROS has been linked to the etiology of different types of human cancer [23, 36]

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PMID 19342169