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Traumatic stress causes distinctive effects on fear circuit catecholamines and the fear extinction profile in a rodent model of posttraumatic stress disorder

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Network-based drug repurposing has leveraged betweenness and closeness centrality to rank pathway significance and predict drug-disease associations 33,34 , while centrality metrics have also been used to examine disease co-occurrence and mechanistic overlaps 19,35

IGF-1 LR3 is widely used in vitro to explore cell growth, survival, and differentiation , particularly in skeletal muscle, fibroblast, and neuronal models

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