does semaglutide start working immediately When Working? Timeline & Results Weight loss isn't one-size-fits-all. Bio-individuality

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The need for long term use to avoid regaining weight The STEP 4 study revealed two very important findings, the first demonstrated that patients will lose substantial amounts of weight during the 16-week upward titration period but will not achieve their maximum weight loss until taking the full dose for 1 year

doi: 10.1038/emboj.2008.52

If you do not feel a difference in the first few days after starting, that is normal, not a sign the medication is not working