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Protein concentrations were again determined spectrophotometrically at 280 nm

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In a Bio-find cohort consisting of 46 PD patients and 45 healthy controls, a composite biomarker, consisting of t- -Syn, anti-proteinase K (PKres) -Syn, and p--Syn (PSer 129), was a strong indicator of differentiating PD patients from controls, with an area under the curve (AUC) of 0.81

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