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Intracerebroventricular injection of resveratrol ameliorated A-induced learning and cognitive decline in mice

In some embodiments, the otic formulation or composition comprises between about 0.01% to about 50% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof

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We also observed increased aggregate formation following incubation of the GST fusion proteins with cell lysate, which appears to depend on both the cell type and experimental conditions