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In the United States alone, more than 200,000 people suffer from PD (Mollenhauer and von Arnim, 2022

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Change in Hunger Scores After 14 Weeks of Setmelanotide Treatment Compared to Placebo Among pivotal patients with BBS aged greater than or equal to 12 years without cognitive impairment, patients treated with setmelanotide (N = 5) had a greater reduction in hunger score than patients treated with placebo (N = 9) in the mean change in average daily hunger score and most or worst hunger score from placebo-controlled baseline to week 14