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Patients who may particularly benefit from GLP-1 receptor agonists include those with type 2 diabetes and established cardiovascular disease, obesity, or chronic kidney disease (where SGLT2 inhibitors are not suitable or as additional therapy)

It also has mild anti-inflammatory effects and may improve blood lipid profiles in some people

Therefore, retatrutide is not indicated for individuals under 18 years of age

These agents work by enhancing insulin secretion, suppressing appetite, and slowing gastric emptying

Whether that is better or worse than their existing insurance options will depend on their coverage

The plan also addresses a longstanding pricing problem