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The question, as always, is whether these drugs actually work well enough to justify the comparison
The iron chelator deferasirox causes severe mitochondrial swelling without depolarization due to a specific effect on inner membrane permeability
Cui Z, Li Z, Zhang Y, Wang X, Li Q, Zhang L, et al
Nishiwaki H, Ito M, Ishida T, Hamaguchi T, Maeda T, Kashihara K, et al
The right dosing schedule can only be determined through medical supervision and ongoing monitoring
In contrast, quinoline and artemisinin-based antimalarial drugs showed strong effects on the parasites' E GSH after longer incubation times (24 h)
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