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This can be explained by our decision to follow the most detailed (to our knowledge) approach to glucose transport in the brain available in the literature (86, 98)compartmentalizing arterial, capillary, basal lamina, interstitial space, astrocytes, and neuron spaces with glucose transfer between these compartments, described by rates that consider intracellular/extracellular concentration-dependent trans-acceleration and asymmetry of transporters

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Brain Res 710: 229233