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TCMs also regulate amino acid metabolism: Huangqin Tang (HQT) alleviates and delays colitis-associated cancer (CAC) by maintaining amino acid homeostasis and modulating the PI3K/AKT/mTOR pathway, thereby balancing proliferation and apoptosis (120)

Cisplatin can strongly bind to mercaptan metabolites produced by GGT-mediated GSH cleavage, reducing Pt ion entry into cells and inactivating Pt drugs outside the cell (136)

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After achieving their weight-loss goals, a lower maintenance dose may help support appetite control and long-term weight stability