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To address the critical issue of BBB permeability, studies using [H]Dihexa and [C]inulin in rats revealed that Dihexa avidly concentrated in all examined brain regions including the prefrontal cortex, hippocampus, hypothalamus, striatum, thalamus, midbrain, brain stem, and cerebellum, compared to blood

2021;34: e14776

Supplied as a lyophilized powder in vials (5 mg and 10 mg)

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A TUE would be granted if the criteria outlined in the International Standard for Therapeutic Use Exemptions are met

Effects of N-acetylcysteine on outcomes in chronic obstructive pulmonary disease (bronchitis randomized on NAC cost-utility study, BRONCUS): a randomised placebo-controlled trial