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Moreover, although preclinical studies have yielded promising results, large-scale, double-blinded clinical trials remain necessary to verify the therapeutic efficacy and feasibility of these approaches in DN patients

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for instance, the Met35 residue of A, along with upregulated oxidases such as NADPH oxidases and monoamine oxidase B (MAO-B), increase ROS production

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KPV (10 mg per vial) KPV is a tripeptide (Lys-Pro-Val) and the C-terminal fragment of alpha-MSH