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trial participants should contact their trial team, and anyone experiencing severe symptoms should call 999 or attend A&E immediately

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No, swollen lymph nodes are not listed as a recognised adverse effect of tirzepatide in the Summary of Product Characteristics or clinical trial data

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In fact, only a modest improvement in insulin resistance was consistently detected in PWA mice following treatment with metformin, as reflected by a moderately reduced HOMA-IR index

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