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More information on exercise and arthritis

Higher HbA1c levels have also been correlated with reduced hippocampal volume, suggesting that metabolic dysregulation in diabetes may have direct neuroanatomical consequences contributing to depressive symptoms [103]

Obesity-induced and weight-loss-induced physiological factors affecting weight regain

Source: Centers for Disease Control and Prevention

It signals the pancreas to release insulin, helps cells absorb glucose, slows down how quickly food leaves the stomach, and sends signals to the brain to reduce appetite