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Description

These linkers include the GFLG peptide which is cleaved by cathepsin B 75 , the PLGLAG peptide which is cleaved by matrix metalloprotease (MMP)-2/9 76 , and the oxime-hydrazone bond which is hydrolyzed in an acidic pH 77

This was particularly notable because semaglutide 2.4mg, used alone, already represents one of the most effective pharmacological weight loss treatments available