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The MTHFR gene contains the DNA code to produce the MTHFR enzyme

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Whereas no current markers have been shown to predict behavior, Moore and colleagues recently demonstrated that a four-probe fluorescent in situ hybridization (FISH) assay correctly identified 83.8 % of melanomas and additionally detected genetic abnormalities in 6.3 %, 6.7 %, and 10.3 % of nevi with mild, moderate, and severe histopathologic atypia, respectively [43]