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Glucose transport and utilization in the hippocampus: from neurophysiology to diabetes-related development of dementia

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In AD astrocytes derived from pluripotent stem cells pharmacological activation of NRF2 ameliorated amyloid secretion and reduced inflammatory cytokine expression ( NLGF ), increased expression of NRF2 reduced inflammation and oxidative stress and improved cognition (Uruno et al., 2020)