In this study, a total of 600 participants are randomized
Beyond the absolute contraindications, several situations call for heightened caution in the class framing and are firmly a clinicians domain: a history of pancreatitis or symptomatic gallstones, significant gastrointestinal motility disorders (such as gastroparesis, which slowed gastric emptying can worsen), diabetic retinopathy that is not stabilized, severe renal impairment where dehydration from GI side effects raises risk, and any concurrent use of insulin or a sulfonylurea, where the additive glucose-lowering can produce hypoglycemia
Prevalence estimates vary by study, but ITP occurs more often in patients with celiac disease than in the general population, and screening is reasonable in otherwise unexplained ITP
Properly manufactured GLP-1 injections should appear clear and colorless Cloudy, yellow, or brown discolorations indicate possible degradation or contamination and warrant immediate discontinuation
Store the product in a cool, dry place in a well sealed package out of reach for children under 3 years
10.1016/S2214-109X(13)70145-1 344 World Health Organization (2014)
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