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Scientific and regulatory perspectives in herbal and dietary supplement associated hepatotoxicity in the United States

Key Takeaway: The demand for GLP-1 drugs is rising sharply, and employers and health plans are seeing it in rising costs

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The popularity of GLP-1 medications for weight loss caused major shortages of these medications and higher prices

Even with an FDA-approved weight loss indication, most insurers classify Wegovy as a lifestyle medication rather than a medically necessary treatment and deny claims

Notably, the tumors in Exe-9-treated mice were markedly smaller compared with those in the control group (Fig