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The number of people living with diabetes rose from 200 million in 1990 to 830 million in 2022, with the steepest rises in low- and middle-income countries

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As a result of that, initial recommendations focus on the use of metformin or a thiazolidinedione if metformin is contraindicated, followed by a GLP-1 agonist or a DPP-4 inhibitor