GLP-1 Agonists Show Promise in Treating Substance Use Disorders Nov 7, 2025 5 min read Updated: Dec 17, 2025 In recent years, medications originally developed to treat Type 2 diabetes, obesity, and other weight-related conditionssuch as semaglutide and liraglutideare showing promise in treating substance use disorders (SUDs)
In addition, many questions remain about the long-term effectiveness and risks of these drugs as well as whether there are differences between GLP-1 formulations
Moreover, early clinical trials and real-world evidence have shown promising results regarding Semaglutides safety, tolerability, and efficacy in lupus patients, suggesting its potential as an adjunctive therapy in comprehensive lupus management
Theyre not FDA-approved, which means theres no federal oversight of testing or consistency
Inadequate responders (2-5% body weight loss) You lost some weight, maybe 10 to 15 pounds over six months
Dose Flexibility Some providers offer more flexibility in dosing adjustments, potentially affecting pricing structures