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The supporters of coffee enemas often tout the antioxidant or anticancer properties of coffee enemas by claiming the cafestol palmitate in coffee promotes glutathione S-transferase, which detoxifies the products of tumour cell metabolism, and that the enema fluid stimulates movement of the colon and drainage of toxic substance from the gut

10.1016/j.toxlet.2021.04.018 29 GabayC.SmithM.EidlenD.ArendW

Effects of ethyl p-chlorophenoxyisobutyrate on carbohydrate and fatty acid metabolism in rat liver

Significantly decreased protein expression of SOD1 and SOD2 was reported in HFD-fed mice (Chen et al

The body can convert GSSG back into the active GSH form using an enzyme called glutathione reductase, provided there are adequate levels of NADPH, a compound integral to many cellular processes, including the antioxidant response

10.1007/s000180050041 24 DavletovaS.RizhskyL.LiangH.ShengqiangZ.OliverD