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Fenfluramine and dexfenfluramine, which had the serious side effect of creating high blood pressure in the lungs, were combined with the amphetamine derivative phentermine to create a drug widely known as fen-phen, which produced weight loss and damage to heart valves

10.1161/hh0102.102330 Circ Res

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Despite the previous hypothesis that the inner mucus layer in the colon is devoid of bacteria in healthy subjects, it has been shown that Acinetobacter spp and Proteobacteria are able to associate with the colonic crypt [7]

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