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En los estudios LEAD (Liraglutide Effect and Action in Diabetes), concretamente en el LEAD-1 y 216,17, la dosis de liraglutida 1,80mg logr reducciones de HbA1c de 1,10 y 1,00%, respectivamente

The underlying pathophysiological mechanisms have not been elucidated in depth

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1 The discovery of vascular receptors that control vessel tone and neurohumoral mediators in hypertension has led to the development of modern antihypertensive drugs such as beta-blockers, angiotensin converting enzyme inhibitors, AT-1 receptor blockers or calcium channel blockers