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For people coming from high-dose semaglutide (2.4 mg weekly), the same principle applies

For researchers and clinicians following this issue, this is the central question in the upcoming FDA decision: is dysesthesia frequent and debilitating enough to justify a special mention in the indications, or even a 12 mg dose reserved for specific patients

For individuals who only start, the starting dose of Ipamorelin is recommended between 200 and 400 mcg per day