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98.Loh JS, et al

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To confirm that the reduced efficacy of glibenclamide and tolbutamide to stimulate insulin secretion in -barr1-KO mice in vivo was indeed caused by signaling deficits in pancreatic cells, we performed a series of islet perifusion studies

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Clinical studies suggest that GLP 1 & GIP therapy may be even more effective than GLP 1 alone, with patients often experiencing greater weight loss in a shorter period

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