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thaliana mPGES-2 is the most significantly regulated gene in response to environmental stresses among Cys-GSTs

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Furthermore, AgRP neurons send potent inhibitory projections [via gamma-aminobutyric acid (GABA)] directly onto POMC neurons, providing a second, parallel mechanism to suppress satiety signaling and promote a robust orexigenic drive [11]

This mitochondrial malfunction then leads to compensatory increase of glycolysis [21]

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