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compounds are investigational outside approved indications

Those are precisely the questions the larger, longer Phase 3 TRIUMPH program is designed to answer, which is why an approval decision waits on it

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Free copper then oxidizes surrounding ingredients or the peptide backbone itself, producing brown discoloration

Spectrochim Acta Part A Mol Biomol Spectrosc 90:158164 Wang Y, Liu S, Liu Z, Yang J, Hu X (2013) Study on the interactions of antiemetic drugs and 12-tungstophosphoric acid by absorption and resonance Rayleigh scattering spectra and their analytical applications