The effluent was ionized via ion electrospray in negative mode on a TSQ Quantiva triple-quadrupole mass spectrometry with the following instrument settings: ion spray voltage 2500 V, sheath gas 28, ion transfer tube temperature 325, aux gas 8, and FWHM of 0.7 for both Q1/Q3 resolution
Imaging pain in the brain: the role of the cerebral cortex in pain perception and modulation
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Ongoing research continues to reveal the complex roles of GPx enzymes in health and disease, particularly in their involvement in cancer, neurodegenerative disorders, and the aging process [10]
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The TNF-like weak inducer of apoptosis (TWEAK)/fibroblast growth factor-inducer 14 (Fn14) pathway and downstream effectors like cAMP response element binding protein (CREB) are implicated, but effective targeted therapies are lacking