Important context: compounded medications are not FDA-approved, and the FDA does not verify their safety, quality, or potency
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Ozempic, while originally FDA-approved for managing type 2 diabetes, is now increasingly prescribed off-label for weight loss in patients without diabetes
For patients already on a GLP-1 medication, the eloralintide news does not change today's plan
Previously, the ACHIEVE-1 study evaluated orforglipron monotherapy in people with early type 2 diabetes uncontrolled with lifestyle intervention, and demonstrated a 12 mmol/mol (1.1%) greater HbA 1c reduction and a 5.9% greater body weight reduction than placebo (Rosenstock et al, 2025)
When starting any medication, its important to examine how it may interact with your lifestyle as a whole