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Pain and Discomfort : Lipedema can be associated with pain, discomfort or a feeling of heaviness in the affected areas, which can be constant or occur from time to time

This makes oral administration an interesting choice for those dealing with stress-induced GI dysfunction or inflammatory bowel conditions linked to mood disorders

Zaboli et al., 2021)

Consistently, the protein expression levels of HO-1, Nrf2, and Keap1 were also significantly increased in the DZN-treated group compared to those in the control group (Fig

doi: 10.1186/s12951-025-03901-1 44 ZhangSLiDFanMYuanJXieCYuanHet al

Increased hair loss may result from cortisol