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Restoration of autophagy by puerarin in lead-exposed primary rat proximal tubular cells via regulating AMPK-mTOR signaling

Minimizing Aspiration Risk: Use preoperative liquid diet (at least 24 hours) in patients with concern for delayed gastric emptying

Santos-Reboucas, C

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The therapeutic effects arise through three primary mechanisms: central appetite suppression via hypothalamic GLP-1R activation (reducing food intake by 20-35%), delayed gastric emptying through vagal pathways (enhancing satiety per meal), and glucose-dependent insulin secretion from pancreatic beta cells (improving glycemic control)