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Similarly, trials of semaglutide have shown substantial reductions in waist circumferencea clinical surrogate for visceral adiposityalongside improvements in cardiometabolic markers including hemoglobin A1c, blood pressure, and lipid profiles
These results support the emerging understanding that GLP-1 RAs have anti-inflammatory and antioxidant properties that help reduce oxidative stress and inflammationtwo major contributors to kidney damage
Schwabe, A
There is harm to losing and regaining, and we have to be really careful not to use these drugs as a crash diet
Conceptual Origin: From Empirical Observation to Theoretical Framework In the 16th century, the Swiss physician Paracelsus established the philosophical foundation for dose-response relationships with his statement, The dose makes the poison ( Sola dosis facit venenum )
28 JoshiG.HardasS.SultanaR.St ClairD
