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Semaglutide Targets One Hormone, While Tirzepatide Targets Two Semaglutide focuses solely on GLP1: This hormone slows digestion, reduces hunger, and helps control blood sugar, which creates a steadier rhythm for how your body processes food

10.3389/fmed.2023.1015711 115 PatelT.ZhouJ.PiepmeierJ

San Antonio Metabolism study