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Diagnosis is made by measuring the concentration of different metabolites in the gamma-glutamyl cycle, enzyme activity and in glutathione synthetase and gamma-glutamylcysteine synthetase deficiency, also by mutation analysis

Dating back to ancient Greece, the herb rosemary has a long history of traditional use

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Copper peptides are sensitive to oxidation and light degradation

578 Pharmacological treatments include cholinergic agonists, such as bethanechol, to stimulate detrusor muscle contraction, antimuscarinic agents, such as oxybutynin or tolterodine, for overactive bladder symptoms, and beta-3 agonists, such as mirabegron, to relax bladder smooth muscle during the storage phase

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