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To our knowledge, this is the first time a reduced FABP1 expression in response to direct activation of the GLP-1R is shown in hepatocytes

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Mounjaro directly targets this gut-brain communication

Reducing intestinal barrier permeability attenuates arthritis Since our results suggested that increased zonulin levels along with impaired intestinal permeability for lactulose and FITC-Dextran (FD4) are preceding the onset of murine and human arthritis, we sought an intervention that strengthens the intestinal barrier and may disrupt the transition from autoimmunity to inflammation and thereby inhibit the onset of arthritis

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