Confirmatory diagnostic studies should be performed prior to initiating therapy, if possible, and the patient should be followed with appropriate studies to demonstrate hematologic improvement (Hgb, hematocrit, RBC, reticulocyte count)
Look at the sheer number of people affected
Abstract Background A meta-analysis is presented of cardiovascular outcome trials (CVOTs) comparing glucagon-like peptide-1 receptor agonists (GLP-1RA) versus placebo on cardiorenal outcomes in patients with type 2 diabetes mellitus (T2DM)
GLP-1s do "much, much more than weight loss," study author Dr
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Although preliminary in vivo studies have shown tumor suppression without significant weight loss in mice, extensive toxicology profiles are required to rule out off-target effects, particularly the neurotoxicity and myelosuppression typically associated with tubulin inhibitors (115)