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David Knopman, a neurologist at the Mayo Clinic in Rochester, Minnesota, said it is "totally unknown what the link is between the GLP-1 target in the brain and Alzheimer's pathology, and that is not a good sign." There are currently two drugs approved for slowing Alzheimer's by removing amyloid from the brain, Lilly's Kisunla and Leqembi from Eisai and Biogen