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Fulop et al., 2021)

This demonstrates that standard doses can be lethal in metabolically vulnerable pregnant women

Urinary F2-isoprostane is the gold standard marker of lipid peroxidation, reliable for assessing oxidative stress

In ALD, ethanol metabolism via hepatocyte CYP2E1 generates excess ROS and acetaldehyde, inducing endoplasmic reticulum stress and mitochondrial dysfunction [365]