Periodic blood work helps monitor ongoing response and safety
The former increases appetite and the latter suppresses appetite, both of which are critical for the metabolic homeostasis of the body (128)
Cost Comparison vs Alternatives Wegovy oral, NovoCare: $149/mo (most affordable FDA-approved GLP-1 weight-loss option) Wegovy injection, NovoCare: $349/mo Zepbound, LillyDirect: $399/mo (higher efficacy: ~20% vs ~15%) Saxenda, no comparable program: ~$1,349/mo retail (~8% efficacy) See our full GLP-1 cost guide for the broader comparison
Lastly, a manufacturer (Bausch Health) recently pulled out of the MDRP, meaning their drugs will likely no longer be covered by state Medicaid programs (as states will no longer receive rebates), which raises concerns for enrollee access to prescription drugs, especially if more manufacturers follow suit
While incretin-based therapies have been commercially available since 2005, most clinical trials only report short term outcomes
TSI is an antibody that mimics the actions of thyroid-stimulating hormone (TSH), which causes the thyroid to make more of the thyroid hormones, T3 and T4