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The Microneedle has the potential to pierce the stratum corneum, generating channels for the drug molecule to quickly diffuse beneath the epidermis

MALDI-TOF or ESI-MS confirms [M+H]+ = 711.9 m/z

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Patch-clamp electrophysiological recordings NG neurons were perfused in the bath solution (Composition in mmol L 1 : NaCl 126.2, KCl 3.1, MgCl 2 2, CaCl 2 2, HEPES 10, glucose 10

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