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Despite this, NHEJ is still used more commonly than HR in human cells

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For example, siTGF-PLP-Nesn anoparticles composed of neutrophils (NEs) and cationic liposomes carrying paclitaxel/TGF- (TGF-) siRNA, can also target tumor sites and prevent tumor-associated neutrophils from transitioning from an anti-tumor (N1) phenotype to a pro-tumor (N2) phenotype thereby enhancing anti-tumor immunity and inhibiting tumor growth (114)

Studies in the AOP provide evidence of upstream KEs observed at the same doses or lower doses as the downstream KEs

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According to a study conducted by Rajabi et al